Journal of the European Optical Society - Rapid publications, Vol 8 (2013)

Self-tuning laser speckle contrast analysis based on multiple exposure times with enhanced temporal resolution

D. Zölei, T. Smausz, B. Hopp, F. Bari

Abstract


Laser Speckle Contrast Analysis (LASCA) was introduced in 1981. Since then, several enhancements were applied to it. Nowadays, thetechnique can provide relatively high accuracy as well as high temporal and spatial resolution during the examination of ocular or cerebraltissues. However, in the case of skin, the results are highly affected by the intensive scattering on the skin surface, as the scattering onthe non-moving parts of the sample lead to the detrimental decrease of the accuracy. We present a LASCA method based on the use ofmultiple exposure times, combined with the switching-mode control of the light intensity and a special sampling technique to achieve nearto real-time measurement of the skin perfusion. The system based on our method is able to automatically handle the destructive effect ofthe skin surface and re-tune itself according to the changes of the sample, while it provides full-field perfusion maps with high accuracy,without the need of any precalibrations.

© The Authors. All rights reserved. [DOI: 10.2971/jeos.2013.13053]

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